Job Description

Kelly Government Solutions is a strategic supplier and business partner to the federal government and its key suppliers. Kelly Government Solutions offers scientists the opportunity to support basic and applied research projects designed to protect our military and nation from current and emerging biological threat agents. We are seeking Lead Genomics Laboratory Technician to provide laboratory support within a Department of Defense laboratory in Frederick, MD. Please note: this position is contingent upon contract award.

This is a long-term contract position which offers:

• Competitive compensation and comprehensive benefit package
• Optional health, vision, and dental plans
• Paid leave as well as 11 paid federal holidays and 401K plan.
• Professional development program for continuing job-related education/training

MAJOR RESPONSIBILITES

• Provide laboratory support for research efforts within the Center for Genome Sciences in the Molecular Biology Division.
• Conduct basic and applied research on current and emerging threats in support of the biodefense and infectious disease program.
• Aid in the execution of scientific studies including extraction of nucleic acids from different biological matrices, quantification and quality of RNA and DNA, PCR amplification, sequencing library preparation and quantification, high-throughput screening assays and/or high-throughput sequencing on infectious agents.
• Support the processing of tissues from animals, data analysis and maintaining laboratory areas and equipment.
• Provide supervisory support to junior contract personnel, train new personnel, and perform routine laboratory safety inspections for assigned areas.
• Work on automation equipment that can handle and process high numbers of samples such as Hamilton STAR and King Fisher liquid handlers.
• Perform purification of nucleic acids from inactivated viral cultures, animal tissues and human subject blood. Assist with design and performing nucleic acid-based assays for tissue culture and/or animal tissue samples.
• Operate and manage sequencing platforms including Illumina and Oxford Nanopore Technologies.
• Conduct nucleic acid extraction, bioanalysis, quantitation, and perform PCR/qPCR.
• Perform cloning, primer design, Gibson Assembly, restriction enzyme digestion, ligation, site-directed mutagenesis, and transcription processes.
• Analyze data from Western Blot equipment, Real-Time PCR systems, and sequencing assays.
• Maintain and manage mammalian cell cultures in multiple biosafety levels (BSL-2, BSL-3, BSL-4).
• Use RNAseq protocols to study gene expression and identify signaling pathways for treatment strategies.
• Conduct population genomics and whole genome sequencing for pathogen analysis.
• Write and review SOPs and ensure adherence to Good Laboratory Practice (GLP) and compliance standards.
• Manage laboratory supplies, inventory, and regulatory compliance.

REQUIREMENTS

• Bachelor or master's degree in Biology or related scientific discipline
• Minimum of 5 years of laboratory research experience with a focus on cell and molecular biology techniques such as cell culture, PCR, sequencing, NGS library preparation, and assay design.
• Must be comfortable working with animal models for studies and handling bacterial and viral pathogens for in vitro and in vivo studies
• Willing and able to work in BSL-2, BSL-3, and BSL-4 biocontainment labs, which requires eligibility and enrollment in the Biological Personnel Reliability Program (BPRP).
• Per contract guidelines, US citizenship is required.

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